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In theory, the approach sounds quite simple: find a protein that cancer cells absolutely need to survive and develop an active ingredient that initiates the destruction...
Signal transduction is a highly complex matter in cells. TGF-ß regulates many cell functions during human and animal development, but also in the adult organism. How...
The cells of certain tumors, the “neuroblastomas,” divide very quickly. This causes them problems that can be fatal for them. A new study shows how they...
Merck and Pfizer Inc. announced that the US Food and Drug Administration (FDA) has accepted for Priority Review the supplemental Biologics License Application (sBLA) for Bavencio...
Merck and AstraZeneca’s Lynparza has been approved by the FDA for first-line maintenance therapy of BRCA-mutated ovarian cancer. “Lynparza is now the first PARP inhibitor to...
Immuno-oncology (I-O) drug development will remain at the forefront of the pharmaceutical industry in 2019, says GlobalData, a data and analytics company. The company’s latest annual...
Merck and Pfizer Inc. announced that data from a planned interim analysis of the Phase III Javelin Ovarian 100 study of avelumab did not support the...
Following the news that the combination did not improve overall survival versus standard-of-care chemotherapy in metastatic head and neck cancer previously treated with platinum-based chemotherapy, it...
Merck, a science and technology company, announced that the US Food and Drug Administration (FDA) has granted orphan drug designation (ODD) to M7824, the first regulatory...
