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Home Focus Pharmaceuticals

New filling and closing machine

28. September 2017
in Pharmaceuticals
Compact design for higher efficiency: the AFG 5000

Compact design for higher efficiency: the AFG 5000

As part of an exclu­sive machine pre­sen­ta­tion in Crail­sheim from Sep­tem­ber 18 through 29, 2017, Bosch Pack­ag­ing Tech­nol­o­gy intro­duced the lat­est addi­tion to its AFG series. The fill­ing and clos­ing machine for phar­ma­ceu­ti­cal pow­ders in glass vials offers man­u­fac­tur­ers a wide range of options. “Dur­ing devel­op­ment, our main focus was on flex­i­bil­i­ty,” explains Dieter Band­tel, prod­uct man­ag­er at Bosch Pack­ag­ing Tech­nol­o­gy. “With the AFG 5000, cus­tomers can choose between sev­er­al dif­fer­ent ver­sions and var­i­ous fea­tures. In addi­tion, we have sig­nif­i­cant­ly increased the out­put rate in the high-per­for­mance segment.

New vari­able trans­port system 

Based on a sin­gle machine plat­form, the sys­tem can accu­rate­ly fill both large and small amounts of pow­der. Cus­tomers have the choice between one fill­ing point for an out­put of 160 con­tain­ers per minute through to three fill­ing points for up to 480 vials per minute. Thanks to the vac­u­um-com­pressed-air fill­ing sys­tem, the out­put remains high even with small fill­ing amounts. For all ver­sions, cus­tomers can choose between sta­tis­ti­cal or 100% in-process con­trol of dos­ing weights.

“To opti­mize effi­cien­cy, we have devel­oped a new, flex­i­ble trans­port sys­tem for the AFG 5000,” says Band­tel. “While the vials are con­tin­u­ous­ly fed into the machine, the trans­port sys­tem adjusts the speed of the fol­low­ing process­es to pre­cise­ly match the rhythm of the indi­vid­ual work sta­tions.” Whether fill­ing, weigh­ing or clos­ing of vials – each stage is opti­mal­ly paced. The new ver­ti­cal trans­port sys­tem was designed to pre­vent idle time or bot­tle­necks. Rotat­ing car­ri­er sys­tems, known as shut­tles, trans­fer the vials quick­ly and safe­ly to the respec­tive work sta­tion. Once the vials have been sealed and tak­en out of the sys­tem, the shut­tles quick­ly return to the infeed, ready for the next trans­port run.

Com­pact and effi­cient design 

In addi­tion to flex­i­bil­i­ty, we par­tic­u­lar­ly focused on com­pact design dur­ing the devel­op­ment of the AFG 5000. “Our cus­tomers’ pow­der fill­ing takes place in class B clean­rooms, where every cen­time­ter counts in terms of oper­at­ing, main­te­nance and clean­ing costs,” explains Band­tel. Apart from the ver­ti­cal design, the sep­a­ra­tion of the com­pact fill­ing sta­tion from the intake and out­put reduced the amount of space that must be cooled and cleaned with ster­ile, dry air. A fur­ther space-sav­ing fea­ture is the option­al air-treat­ment sys­tem, which can be installed out­side the ster­ile area.

All com­po­nents that come into con­tact with the prod­uct can eas­i­ly be dis­as­sem­bled for clean­ing and ster­il­iza­tion. The result is an easy-to use machine with only few for­mat parts, offer­ing cus­tomers sub­stan­tial space- and cost-sav­ings. In line with Bosch’s phar­ma­ceu­ti­cal line com­pe­tence, the AFG 5000 can be com­bined with upstream clean­ing machines and ster­il­iz­ing tun­nels, as well as down­stream cap­ping equip­ment to cre­ate a com­plete line for safe and reli­able fill­ing process­es for phar­ma­ceu­ti­cal powders.

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